Spicy Chicken Sandwich Creamy Sauce

Section: Satisfying Main Dishes for Every Occasion

This spicy chicken sandwich features juicy fillets marinated in buttermilk and bold spices, fried until golden and crispy. The luscious creamy sauce made of mayonnaise, sour cream, hot sauce, and lemon juice brings a tangy and cooling contrast to the fiery coating. Soft buns cradle the chicken, with crunchy lettuce and tangy pickles adding fresh texture. Together, these layers create a balance of heat and smoothness perfect for a satisfying and flavorful handheld meal any day.

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Published By Evelyn
Updated as of Fri, 14 Nov 2025 12:48:55 GMT
A spicy chicken sandwich with creamy homemade sauce. Bookmark
A spicy chicken sandwich with creamy homemade sauce. | foodbymary.com

This spicy chicken sandwich with creamy homemade sauce is the perfect balance of heat and comfort. Crispy chicken fillets coated in bold spices sit inside a soft, pillowy bun with a tangy, cooling sauce that brings everything together. It’s a satisfying meal that works for a busy weeknight or a casual weekend gathering, offering a handheld burst of flavor that never disappoints.

I first made this recipe for a family dinner and everyone was hooked instantly. The crispy chicken and the homemade sauce made the whole meal feel special even though it’s straightforward to whip up.

Ingredients

  • Chicken breasts or thighs: choose thighs for juicier, more flavorful bites or breasts for a leaner option. Pounding them to even thickness ensures perfect cooking
  • Paprika, cayenne, garlic powder, onion powder: these spices create a layered, warm heat. Fresh spices provide the best aroma and punch
  • Buttermilk: tenderizes the chicken and helps the coating stick. Make sure it’s fresh for optimal marinade effect
  • Flour and cornstarch: combine for a light and extra crispy coating. Opt for finely milled flour for a smoother crust
  • Soft buns: essential for a tender, slightly sweet base to offset the heat. Brioche or potato rolls work wonderfully
  • Mayonnaise, sour cream, hot sauce, lemon juice: blended into a creamy sauce that cools and adds tang. Use a quality hot sauce that suits your heat preference
  • Pickles and lettuce: offer crunch and freshness that brighten every bite. Thick-cut pickles and crisp lettuce like iceberg or romaine are ideal

Step-by-Step Instructions

Marinate the Chicken:
Place chicken breasts or thighs in a bowl and cover fully with buttermilk. Add paprika, cayenne, garlic powder, and onion powder to the marinade, mixing well to coat. Allow the chicken to soak for at least an hour, or overnight if you have extra time, to deeply infuse the flavors and tenderize the meat.
Prepare the Coating:
In a shallow dish, mix together flour, cornstarch, paprika, cayenne, salt, and pepper. This combination forms the dry, crispy crust that will surround each chicken piece once fried.
Bread the Chicken:
Take the marinated chicken out and dredge it carefully in the seasoned flour mixture, pressing gently so the coating sticks. For an extra crispy finish, dip the chicken back into the buttermilk once more and coat again in the flour mixture.
Fry Until Golden:
Heat oil in a heavy skillet or deep fryer to approximately 350 degrees Fahrenheit. Fry each chicken piece carefully, cooking for four to six minutes per side depending on thickness, until the crust turns golden and the chicken is cooked through. Transfer to paper towels to drain so the coating stays crisp.
Make the Creamy Sauce:
In a small bowl, whisk together mayonnaise, sour cream, hot sauce, lemon juice, and a pinch of paprika. Taste and adjust seasoning if needed. The sauce should be tangy with just the right level of spice to complement the chicken.
Assemble the Sandwich:
Lightly toast the buns to add a subtle crunch and warmth. Spread a generous layer of the creamy sauce on both halves. Layer with the golden fried chicken, crisp lettuce, and slices of tangy pickles. Cover with the top bun and serve immediately while the chicken is still sizzling and crispy.
A spicy chicken sandwich with creamy homemade sauce. Bookmark
A spicy chicken sandwich with creamy homemade sauce. | foodbymary.com

The creamy sauce is a highlight for me, balancing the bold spices perfectly. I have fond memories of serving this up for a weekend get-together where everyone raved about that zesty kick and smooth finish.

Storage Tips

Keep leftover chicken fillets in an airtight container in the refrigerator for up to three days. Keep the buns and toppings separate to avoid sogginess. When ready to eat, reheat the chicken in an oven or air fryer to restore its crisp texture.

Ingredient Substitutions

If you don’t have buttermilk, you can use milk mixed with a tablespoon of white vinegar or lemon juice to mimic the acidity. Chicken thighs can be swapped for breasts or even chicken tenders for a smaller portion. If you want less heat, reduce the cayenne or omit the hot sauce in the sauce.

Serving Suggestions

Pair your sandwich with classic crispy fries or onion rings for a crunchy contrast. A fresh coleslaw or side salad adds a cool, crisp dimension. Sweet potato fries or creamy mac and cheese are also delightful comfort food companions.

Cultural Background

The idea of spicy fried chicken sandwiches has roots in Southern American cuisine but has evolved with regional spice blends and homemade sauces. The creamy sauce here takes inspiration from mayo-based dressings popular in sandwich shops across the US, bringing a tangy counterpoint to the spicy fried chicken.

Pro Tips

Always pat your chicken dry before coating to help the breading stick better. Don’t overcrowd the pan when frying as it lowers the oil temperature and makes chicken greasy. Toast buns lightly just before assembly to prevent them from getting soggy too quickly.

Common Recipe Questions

→ What chicken cuts work best?

Boneless, skinless breasts or thighs are ideal. Breasts offer leaner texture while thighs stay juicier and more flavorful.

→ How to achieve a crispy coating?

Coating the marinated chicken twice in a seasoned flour and cornstarch mix before frying creates a crunchy, golden crust.

→ What gives the sauce its creamy texture?

A blend of mayonnaise and sour cream creates smoothness, balanced with hot sauce and lemon juice for a tangy kick.

→ How should leftovers be stored?

Keep fried chicken separate from buns and toppings in airtight containers. Refrigerate chicken up to 3 days and sauce up to 5 days.

→ Best ways to reheat the chicken?

Use an oven or air fryer to maintain crispiness. Avoid microwaving as it softens the coating.

→ What sides pair well with this sandwich?

Classic choices include crispy fries, coleslaw, sweet potato fries, onion rings, or a fresh side salad.

Spicy Chicken Sandwich Creamy Sauce

Crispy, spicy chicken paired with a tangy, creamy sauce in a soft bun delivers bold, balanced flavors.

Prep Time
20 minutes
Cooking Time
15 minutes
Complete Time
35 minutes
Published By: Evelyn

Recipe Category: Main Dishes

Skill Level: Moderately Challenging

Cuisine Type: American

Total Portions: 2 Serves How Many (2 sandwiches)

Dietary Preferences: ~

Required Ingredients

→ Chicken

01 450 grams boneless, skinless chicken breasts or thighs

→ Spices

02 1 teaspoon paprika
03 0.5 teaspoon cayenne pepper
04 1 teaspoon garlic powder
05 1 teaspoon onion powder
06 Salt and black pepper to taste

→ Marinade

07 240 milliliters buttermilk

→ Breading

08 120 grams all-purpose flour
09 30 grams cornstarch
10 1 teaspoon paprika
11 0.5 teaspoon cayenne pepper
12 Salt and black pepper to taste

→ Sauce

13 80 grams mayonnaise
14 60 grams sour cream
15 15 milliliters hot sauce
16 15 milliliters fresh lemon juice
17 Pinch of paprika

→ Assembly

18 2 soft sandwich buns
19 Fresh lettuce leaves
20 Pickle slices

→ Frying

21 Vegetable oil for frying

Step-by-Step Instructions

Step 01

Combine chicken pieces with buttermilk, paprika, cayenne, garlic powder, and onion powder in a bowl. Marinate for at least 60 minutes or refrigerate overnight for enhanced flavor and tenderness.

Step 02

In a shallow dish, mix flour, cornstarch, paprika, cayenne, salt, and pepper evenly to create a seasoned coating.

Step 03

Dredge each marinated chicken piece in the flour mixture, pressing gently. For extra crispiness, dip back into buttermilk then coat once more in the flour mixture.

Step 04

Heat vegetable oil to 175°C, then fry chicken pieces for 4 to 6 minutes per side until golden brown and fully cooked. Drain on paper towels to remove excess oil and maintain crispness.

Step 05

Whisk together mayonnaise, sour cream, hot sauce, lemon juice, and a pinch of paprika until smooth. Adjust seasoning as desired.

Step 06

Lightly toast buns, spread creamy sauce on both halves, then layer fried chicken, lettuce, and pickles. Close with the top bun and serve immediately.

Handy Cooking Tips

  1. For best texture, reheat leftover chicken in an oven or air fryer instead of a microwave to retain crispiness.

Necessary Kitchen Tools

  • Frying pan or deep skillet
  • Mixing bowls
  • Shallow dish for breading
  • Tongs or slotted spoon
  • Paper towels

Allergy Details

Always check ingredient packaging for potential allergens and consult a healthcare professional when in doubt.
  • Contains eggs and dairy in the sauce and marinade
  • Contains gluten in the flour

Nutritional Information (Per Serving)

These nutrition details are for guidance and don’t replace professional advice.
  • Calories: 650
  • Fat: 30 grams
  • Carbohydrates: 50 grams
  • Proteins: 35 grams